Background. Even though the benefit of antiretroviral therapy (ART) is well established, there is a regional variation in the extent\nof its benefit. The aim of this review is to highlight mortality and its predictors in Ethiopian adult HIV patients who were on\nART. Methods. Relevant articles were searched on PubMed and Google Scholar databases. The search terms used in different\ncombinations were predictor/determinant/factors, mortality/death/survival, HIV, ART/HAART, and Ethiopia. Result. 5ââ?¬â??40.8% of\nthe patients died during the follow-up period. More than half (50ââ?¬â??68.8%) of the deaths occurred within 6 months of initiating\nART. Advanced stage disease (stage III and stage IV), nonworking functional status (bedridden and ambulatory), low baseline\nCD4 count, low baseline hemoglobin level, TB coinfection, lower baseline weight, and poor treatment adherence were commonly\nidentified as predictors of death in HIV patients. Conclusion. 5ââ?¬â??40.8% of HIV patients in Ethiopia die in 2ââ?¬â??5 years of initiating\nantiretroviral treatment. Most of the deaths in HIV patients occur early in the course of treatment. Special emphasis should be\ngiven for patients with advanced stage disease, nonworking functional status, low baseline CD4 count, low baseline hemoglobin\nlevel, TB coinfection, lower baseline weight, and poor treatment adherence.
Loading....